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NF-kB p65 Recombinant Rabbit Monoclonal Antibody [PSH0-27] (HA721307)

Price: Regular price $385.00

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Catalog# HA721307

Rabbit Monoclonal to NF-kB p65

Tested for

  • WB

  • IHC-P

  • IF-Cell

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

  • Monkey

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Knock-Out or Knock-Down validated
This product has been cited in peer reviewed publications, see list HERE

Safety datasheet

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

NF-kB p65 Recombinant Rabbit Monoclonal Antibody [PSH0-27] (HA721307)

Immunogen

Synthetic peptide within human rela aa 502-551 / 551.

Host

Rabbit

Positive Control

HeLa cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, A431 cell lysate, Raji cell lysate, HL-60 cell lysate, Daudi cell lysate, COS-1 cell lysate, Mouse lung tissue lysate, human breast cancer tissue, human breast tissue, HeLa, NIH/3T3 cells treated with 50μg/mL TNF-α for 20 minutes, PC-12.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH0-27

RRID

AB_3072424

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IHC-P

  • 1:1,000

  • IF-Cell

  • 1:100-1:200

  • FC

  • 1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 65 kDa

Isotype

IgG

TARGET

UNIPROT #

Q04206

PROTEIN NAME

NF-kB p65

SYNONYMS

Avian reticuloendotheliosis viral (v rel) oncogene homolog A antibody;MGC131774 antibody;NF kappa B p65delta3 antibody;nfkappabp65 antibody;NFkB p65 antibody;NFKB3 antibody;Nuclear factor kappaB antibody;Nuclear Factor NF Kappa B p65 Subunit antibody;Nuclear factor NF-kappa-B p65 subunit antibody;Nuclear factor of kappa light polypeptide gene enhancer in B cells 3 antibody;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 antibody;OTTHUMP00000233473 antibody;OTTHUMP00000233474 antibody;OTTHUMP00000233475 antibody;OTTHUMP00000233476 antibody;OTTHUMP00000233900 antibody;p65 antibody;p65 NF kappaB antibody;p65 NFkB antibody;relA antibody;TF65_HUMAN antibody;Transcription factor NFKB3 antibody;Transcription factor p65 antibody;v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)) antibody;V rel avian reticuloendotheliosis viral oncogene homolog A antibody;v rel reticuloendotheliosis viral oncogene homolog A (avian) antibody;V rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B cells 3, p65 antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

Transcription factor p65 also known as nuclear factor NF-kappa-B p65 subunit is a protein that in humans is encoded by the RELA gene. RELA, also known as p65, is a REL-associated protein involved in NF-κB heterodimer formation, nuclear translocation and activation. NF-κB is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc. Phosphorylation and acetylation of RELA are crucial post-translational modifications required for NF-κB activation. RELA has also been shown to modulate immune responses, and activation of RELA is positively associated with multiple types of cancer.

CITATIONS

  • Wu Lianchi,et al

    Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease via gut microbiota and tryptophan metabolism regulation in an aged laying hen model

  • Chen Jialei,et al

    A Rapid Self-Assembling Peptide Hydrogel for Delivery of TFF3 to Promote Gastric Mucosal Injury Repair

  • Xianbin Wang,et al

    VSIG2 as a novel immunosuppressive ligand interacts with Nectin-2 to regulate T cell responses

  • Zhou Yiqing,et al

    Buddleoside-rich Chrysanthemum indicum L. extract modulates macrophage-mediated inflammation to prevent metabolic syndrome induced by unhealthy diet

  • Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65

  • Panlin Tan,et al

    Evaluation of the effect of phellodendrin application on rats creating an experimental model of non-compression lumbar disc herniation on the NF-κB-related inflammatory signaling pathway

  • Intra-bone marrow injection of magnesium isoglyrrhizinate inhibits inflammation and delays osteoarthritis progression through the NF-κB pathway

  • NecroX-5 alleviate lipopolysaccharide-induced acute respiratory distress syndrome by inhibiting TXNIP/NLRP3 and NF-κB

  • MicroRNA-579-3p Exerts Neuroprotective Effects Against Ischemic Stroke via Anti-Inflammation and Anti-Apoptosis

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