RAC1 Recombinant Rabbit Monoclonal Antibody [PSH05-09] (HA722225)

UNIPROT #

P63000

PROTEIN NAME

RAC1

SYNONYMS

Cell migration inducing gene 5 protein antibody;Cell migration-inducing gene 5 protein antibody;MGC111543 antibody;MIG5 antibody;Migration inducing gene 5 antibody;Migration inducing protein 5 antibody;p21 Rac1 antibody;p21-Rac1 antibody;Rac 1 antibody;RAC1 antibody;RAC1_HUMAN antibody;Ras like protein TC25 antibody;Ras related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody;Ras-like protein TC25 antibody;Ras-related C3 botulinum toxin substrate 1 antibody;Rho family small GTP binding protein Rac1 antibody;TC 25 antibody;TC25 antibody

SUBCELLULAR LOCATION

Cell membrane, Cell projection, Cytoplasm, Membrane, Nucleus, Synapse.

FUNCTION

Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells. It is encoded by the RAC1 gene. This gene can produce a variety of alternatively spliced versions of the Rac1 protein, which appear to carry out different functions. Rac1 is a small (~21 kDa) signalling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of GLUT4 translocation to glucose uptake, cell growth, cytoskeletal reorganization, antimicrobial cytotoxicity, and the activation of protein kinases. Rac1 is a pleiotropic regulator of many cellular processes, including the cell cycle, cell-cell adhesion, motility (through the actin network), and of epithelial differentiation (proposed to be necessary for maintaining epidermal stem cells).