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VCAM1 Recombinant Rabbit Monoclonal Antibody [SA05-04] (ET1601-18)

Price: Regular price $385.00

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Catalog# ET1601-18

Rabbit Monoclonal to VCAM1

Tested for

  • WB

  • IF-Cell

  • IF-Tissue

  • IHC-P

  • IP

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

  • Zebrafish

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Knock-Out or Knock-Down validated
This product has been cited in peer reviewed publications, see list HERE

Safety datasheet

Select your chosen country/region

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

VCAM1 Recombinant Rabbit Monoclonal Antibody [SA05-04] (ET1601-18)

Immunogen

Synthetic peptide within human vcam1 aa 690-739 / 739.

Host

Rabbit

Positive Control

C2C12 cell lysate, 3T3-L1 cell lysate, mouse spleen tissue lysate, rat spleen tissue lysate, NIH/3T3 cell lysate, HUVEC, human tonsil tissue, human spleen tissue, mouse spleen tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

SA05-04

RRID

AB_3069600

APPLICATION DILUTION

  • WB

  • 1:5,000-1:10,000

  • IF-Cell

  • 1:1,000

  • IF-Tissue

  • 1:100

  • IHC-P

  • 1:200

  • IP

  • 1-2μg/sample

  • FC

  • 1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 81 kDa

Isotype

IgG

TARGET

UNIPROT #

P19320

PROTEIN NAME

VCAM1

SYNONYMS

CD106 antibody;CD106 Antigen antibody;INCAM 100 antibody;INCAM-100 antibody;L1CAM antibody;MGC99561 antibody;V-CAM 1 antibody;Vascular Cell Adhesion Molecule 1 antibody;Vascular cell adhesion protein 1 antibody;VCAM 1 antibody;VCAM-1 antibody;VCAM1 antibody;VCAM1_HUMAN antibody

TISSUE SPECIFICITY

Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.

POST-TRANSLATIONAL MODIFICATION

Sialoglycoprotein.

SUBCELLULAR LOCATION

Membrane

FUNCTION

Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene. VCAM-1 functions as a cell adhesion molecule. The VCAM-1 protein mediates the adhesion of lymphocytes, monocytes, eosinophils, and basophils to vascular endothelium. It also functions in leukocyte-endothelial cell signal transduction, and it may play a role in the development of atherosclerosis and rheumatoid arthritis.

CITATIONS

  • Huang, F., Liu, X., Xu, S., Hu, S., Wang, S., Shi, D., Wang, K., Wang, Z., Lin, Q., Li, S., Zhao, S., Jin, K., Wang, C., Chen, L., & Wang, F.

    Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

  • Yafei Wu

    Fusobacterium nucleatum stimulates monocyte adhesion to and transmigration through endothelial cells

  • Daisong Li,et al

    Integrated metabolomics and network pharmacology to reveal the mechanisms of Shexiang Baoxin pill against atherosclerosis

  • Jingyi Xu,et al

    Obtusin ameliorates diabetic retinopathy by inhibiting oxidative stress and inflammation

  • Oral administration of MnCl2 attenuated hyperlipidemia-related cardiac remodeling in ApoE−/− mice

  • He Jia,et al

    Unveiling the Impact of Hemodynamics on Endothelial Inflammation-Mediated Hepatocellular Carcinoma Metastasis Using a Biomimetic Vascular Flow Model

  • Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia

  • Peng Sha,et al

    Dipsacoside B ameliorates cognitive impairment in sepsis-associated encephalopathy by reducing Th17 cell infiltration and neuroinflammation

  • Han Sun,et al

    Isoechinulin B, a natural product from Antarctic fungus, attenuates acute liver injury by inhibiting excessive cell adhesion

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