S100A8 Recombinant Rabbit Monoclonal Antibody [PSH09-70] (HA723135)

UNIPROT #

P05109

PROTEIN NAME

S100A8

SYNONYMS

Calgranulin-A antibody;Calprotectin L1L subunit antibody;CFAG antibody;Cystic fibrosis antigen antibody;Leukocyte L1 complex light chain antibody;Migration inhibitory factor-related protein 8 antibody;MRP-8 antibody;N-terminally processed antibody;p8 antibody;Protein S100-A8 antibody;S100 calcium-binding protein A8 antibody;S100A8 antibody;S10A8_HUMAN antibody;Urinary stone protein band A antibody

SUBCELLULAR LOCATION

Secreted; Cytoplasm; Cytoplasm, cytoskeleton; Cell membrane.

FUNCTION

S100 calcium-binding protein A8 (S100A8) is a protein that in humans is encoded by the S100A8 gene.It is also known as calgranulin A.The proteins S100A8 and S100A9 form a heterodimer called calprotectin.The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis and post COVID-19 condition.