Skip to content

Contact

(857) 353-6600

orders@huabio.com

Osteopontin Rabbit Polyclonal Antibody (ER1802-16)

Price: Regular price $315.00

Volume

Bulk Order Quote   |   Customization Request

Catalog# ER1802-16

Rabbit Polyclonal to Osteopontin

Tested for

  • IF-Cell

  • IHC-P

  • ELISA

Reacts with

  • Human

  • Mouse

This product has been cited in peer reviewed publications, see list HERE

Safety datasheet

Select your chosen country/region

Specifications

Product Type

Rabbit polyclonal primary

Product Name

Osteopontin Rabbit Polyclonal Antibody (ER1802-16)

Immunogen

Synthetic peptide within mouse osteopontin 17-100.

Host

Rabbit

Positive Control

HepG2, MCF-7, human liver cancer tissue, human kidney tissue, mouse kidney tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3069113

APPLICATION DILUTION

  • IF-Cell

  • 1:50-1:200

  • IHC-P

  • 1:50-1:200

  • ELISA

  • 1:5,000-1:10,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 35 kDa

Isotype

IgG

TARGET

UNIPROT #

P10451

PROTEIN NAME

Osteopontin

SYNONYMS

BNSP antibody;Bone sialoprotein 1 antibody;BSP I antibody;BSPI antibody;Early T lymphocyte activation 1 antibody;ETA 1 antibody;ETA1 antibody;MGC110940 antibody;Nephropontin antibody;OPN antibody;Osteopontin antibody;osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein antibody;OSTP_HUMAN antibody;PSEC0156 antibody;secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) antibody;Secreted phosphoprotein 1 antibody;SPP 1 antibody;SPP-1 antibody;SPP1 antibody;SPP1/CALPHA1 fusion antibody;Urinary stone protein antibody;Uropontin antibody

SEQUENCE SIMILARITIES

Belongs to the osteopontin family.

TISSUE SPECIFICITY

Bone. Found in plasma.

POST-TRANSLATIONAL MODIFICATION

Extensively phosphorylated by FAM20C in the extracellular medium at multiple sites within the S-x-E/pS motif.; O-glycosylated. Isoform 5 is GalNAc O-glycosylated at Thr-59 or Ser-62.

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Osteopontin (OPN), also designated bone sialoprotein 1, urinary stone protein, spp-1, Eta-1, nephropontin and uropontin, is an extracellular matrix cell adhesion phosphoglycoprotein. OPN is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans and between collagen fibrils of fully matured hard tissues. While OPN is a major product of osteoblasts, it is also synthesized by brain and kidney cells. OPN isolated from or secreted by various tissues ranges in molecular weight due to posttranslational modifications. OPN functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.

CITATIONS

  • Qing Wang,et al

    S100A9 promotes renal calcium oxalate stone formation via activating the TLR4-p38/MAPK-LCN2 signaling pathway

  • Single-Cell RNA Sequencing Unravels Distinct Tumor Microenvironment of Different Components of Lung Adenocarcinoma Featured as Mixed Ground-Glass Opacity

  • Peng Zhiwei,et al

    Crosstalk between cancer-associated fibroblasts and myeloid cells shape the heterogeneous microenvironment of gastric cancer

  • Xuewu You ,et al

    Single-cell characterization of intra-tumoral heterogeneity and the immunosuppressive microenvironment in uterine serous carcinoma

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now