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Kidins220 Mouse Monoclonal Antibody [3-B6] (M0910-4)

Price: Regular price $350.00

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Catalog# M0910-4

Mouse Monoclonal to Kidins220

Tested for

  • WB

  • IF-Cell

  • IHC-P

Reacts with

  • Mouse

  • Human

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Specifications

Product Type

Mouse monoclonal primary

Product Name

Kidins220 Mouse Monoclonal Antibody [3-B6] (M0910-4)

Immunogen

Recombinant protein with human kinase d-interacting substrate 220 aa 1601-1771 / 1,771.

Host

Mouse

Positive Control

K562 cell lysates, F9 cells, mouse brain tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

3-B6

RRID

AB_3073004

APPLICATION DILUTION

  • WB

  • 1:1,000-1:10,000

  • IF-Cell

  • 1:100

  • IHC-P

  • 1:50

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 197kDa

Isotype

IgG1

TARGET

UNIPROT #

Q9ULH0

PROTEIN NAME

Kidins220

SYNONYMS

Ankyrin repeat-rich membrane-spanning protein antibody;arms antibody;KDIS_HUMAN antibody;kidins220 antibody;Kinase D interacting substance of 220 kDa antibody;Kinase D-interacting substrate of 220 kDa antibody;rgd 619949 antibody

SUBCELLULAR LOCATION

Cell membrane

FUNCTION

Kinase D-interacting substrate 220 (Kidins220), also known as ARMS (ankyrin-rich membrane spanning) is an integral plasma membrane protein predominantly expressed in brain and neurons that presents a polarized location in neural cells, concentrating at the tip of extending neurites and in plasma membrane micro-domains corresponding to lipid rafts. The primary amino acid sequence of Kidins220 reveals 11 ankyrin repeats, 4 trans-membrane domains, a proline-rich region, a sterile-α motif (or SAM) domain, and a type I postsynaptic density-95/discs large/zonula occludens-1 (PDZ)-binding motif at the very C-terminus.

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