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FPR1 Rabbit Polyclonal Antibody (R1511-36)

Price: Regular price $315.00

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Catalog# R1511-36

Rabbit Polyclonal to FPR1

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

  • Mouse

This product has been cited in peer reviewed publications, see list HERE

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

FPR1 Rabbit Polyclonal Antibody (R1511-36)

Immunogen

Synthetic peptide within mouse fpr1 aa 151-200 / 364

Host

Rabbit

Positive Control

NCCIT, MEF, HES, human tonsil tissue, human spleen tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073380

APPLICATION DILUTION

  • WB

  • 1:500

  • IHC-P

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

38 kDa

Isotype

IgG

TARGET

UNIPROT #

P21462

PROTEIN NAME

FPR1

SYNONYMS

fMet Leu Phe receptor antibody;fMet-Leu-Phe receptor antibody;FMLP antibody;fMLP receptor antibody;FMLPR antibody;Formyl peptide receptor 1 antibody;FPR 1 antibody;FPR antibody;FPR receptor antibody;FPR1 antibody;FPR1_HUMAN antibody;N formyl peptide chemoattractant receptor antibody;N formyl peptide receptor antibody;N formylpeptide chemoattractant receptor antibody;N-formyl peptide receptor antibody;N-formylpeptide chemoattractant receptor antibody

SEQUENCE SIMILARITIES

Belongs to the G-protein coupled receptor 1 family.

TISSUE SPECIFICITY

Neutrophils.

POST-TRANSLATIONAL MODIFICATION

Phosphorylated; which is necessary for desensitization.

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.

CITATIONS

  • Song Delei,et al

    Distinct Gene Expression and Immune Features Between Different Neutrophil Extracellular Trap-Related Osteosarcoma Subtypes

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