alpha 1a Adrenergic Receptor Recombinant Rabbit Monoclonal Antibody [JE62-50] (HA720096)

UNIPROT #

P35348

PROTEIN NAME

alpha 1a Adrenergic Receptor

SYNONYMS

ADA1A_HUMAN antibody;ADRA1A antibody;Adra1c antibody;ADRA1L1 antibody;Adrenergic alpha1A receptor antibody;Adrenergic alpha1C receptor antibody;Adrenergic receptor alpha 1a antibody;Adrenergic receptor alpha 1c antibody;Adrenergic, alpha 1A , receptor variant 1 antibody;Adrenergic, alpha 1A , receptor variant 11 antibody;Adrenergic, alpha 1A , receptor variant 3 antibody;Adrenergic, alpha 1A , receptor variant 5 antibody;Adrenergic, alpha 1A , receptor variant 8 antibody;Adrenoceptor alpha 1A antibody;Alpha 1A adrenoreceptor antibody;Alpha 1C adrenergic receptor antibody;Alpha adrenergic receptor 1c antibody;Alpha-1A adrenergic receptor antibody;Alpha-1A adrenoceptor antibody;Alpha-1A adrenoreceptor antibody;Alpha-1C adrenergic receptor antibody;Alpha-adrenergic receptor 1c antibody;Alpha1A adrenergic receptor antibody;ALPHA1AAR antibody;G protein coupled receptor antibody

SUBCELLULAR LOCATION

Cytoplasm, Cell membrane, Nucleus membrane, caveola.

FUNCTION

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.