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Clusterin Rabbit Polyclonal Antibody (ER2001-58)

Price: Regular price $315.00

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Catalog# ER2001-58

Rabbit Polyclonal to Clusterin

Tested for

  • WB

  • IHC-P

  • FC

Reacts with

  • Human

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

Clusterin Rabbit Polyclonal Antibody (ER2001-58)

Immunogen

Synthetic peptide within human clusterin aa350-449.

Host

Rabbit

Positive Control

Hela cell lysate, SKBR-3 cell lysate, human tonsil tissue, human pancreas tissue, A549.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3069535

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:100-1:500

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 52 kDa.

Isotype

IgG

TARGET

UNIPROT #

P10909

PROTEIN NAME

Clusterin

SYNONYMS

40 antibody;AAG 4 antibody;AAG4 antibody;Aging associated protein 4 antibody;Aging-associated gene 4 protein antibody;AI893575 antibody;APO J antibody;Apo-J antibody;APOJ antibody;ApoJalpha antibody;ApoJbeta antibody;Apolipoprotein J antibody;ApolipoproteinJ antibody;CLI antibody;CLU antibody;CLU1 antibody;CLU2 antibody;CLUS_HUMAN antibody;Clusterin alpha chain antibody;Clusterin antibody;Clusterin beta chain antibody;Complement associated protein SP 40 40 antibody;Complement associated protein SP 40 antibody;Complement associated protein SP40 antibody;Complement cytolysis inhibitor a chain antibody;Complement cytolysis inhibitor antibody;Complement cytolysis inhibitor b chain antibody;Complement lysis inhibitor antibody;Complement-associated protein SP-40 antibody;D14Ucla3 antibody;Dimeric acid glycoprotein antibody;Glycoprotein 80 antibody;Glycoprotein III antibody;GP80 antibody;Ku70-binding protein 1 antibody;KUB 1 antibody;KUB1 antibody;MGC24903 antibody;NA1/NA2 antibody;RATTRPM2B antibody;SGP 2 antibody;SGP2 antibody;SP 40 antibody;SP40 antibody;Sugp-2 antibody;Sulfated glycoprotein 2 antibody;Testosterone repressed prostate message 2 antibody;Testosterone-repressed prostate message 2 antibody;TRPM 2 antibody;TRPM-2 antibody;TRPM2 antibody;TRPM2B antibody;Trpmb antibody

SUBCELLULAR LOCATION

Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Membrane, Microsome, Mitochondrion, Nucleus, Secreted.

FUNCTION

Detected in blood plasma, cerebrospinal fluid, milk, seminal plasma and colon mucosa. Detected in the germinal center of colon lymphoid nodules and in colon parasympathetic ganglia of the Auerbach plexus (at protein level). Ubiquitous. Detected in brain, testis, ovary, liver and pancreas, and at lower levels in kidney, heart, spleen and lung.Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis.In humans, clusterin is encoded by the CLU gene on chromosome CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging.

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