ATE1 Recombinant Rabbit Monoclonal Antibody [JE65-47] (HA721061)

UNIPROT #

O95260

PROTEIN NAME

ATE1

SYNONYMS

AI225793 antibody;Arginine tRNA protein transferase 1 antibody;Arginine-tRNA--protein transferase 1 antibody;Arginyl-tRNA--protein transferase 1 antibody;Arginyl-tRNA-protein transferase antibody;Arginyltransferase 1 antibody;Ate1 antibody;ATE1_HUMAN antibody;AW547406 antibody;EC 2.3.2.8 antibody;MGC26724 antibody;OTTHUMP00000020637 antibody;OTTHUMP00000058665 antibody;R transferase 1 antibody;R-transferase 1 antibody

SUBCELLULAR LOCATION

Cytoplasm, Nucleus.

FUNCTION

This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in multiple transcript variants. ATE1 (Arginyltransferase 1) is a Protein Coding gene. Diseases associated with ATE1 include Chromosome 10Q26 Deletion Syndrome and Beare-Stevenson Cutis Gyrata Syndrome. Gene Ontology (GO) annotations related to this gene include arginyltransferase activity. Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues.