PCBP1 Rabbit Polyclonal Antibody (R1608-6)

UNIPROT #

Q15365

PROTEIN NAME

PCBP1

SYNONYMS

Alpha-CP1 antibody;Heterogeneous nuclear ribonucleoprotein E1 antibody;heterogenous nuclear ribonucleoprotein E1 antibody;heterogenous nuclear ribonucleoprotein X antibody;hnRNP E1 antibody;hnRNP-E1 antibody;hnRNP-X antibody;HNRPE1 antibody;HNRPX antibody;nucleic acid binding protein sub 2.3 antibody;Nucleic acid- binding protein SUB2.3 antibody;Nucleic acid-binding protein SUB2.3 antibody;PCBP1 antibody;PCBP1_HUMAN antibody;poly(rC) binding protein 1 antibody;Poly(rC)-binding protein 1 antibody;rCbinding protein 1 antibody

TISSUE SPECIFICITY

Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.

POST-TRANSLATIONAL MODIFICATION

Phosphorylated; lowers poly(rC)-binding activity.

SUBCELLULAR LOCATION

Nucleus. Cytoplasm.

FUNCTION

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD. Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.