Dcp1a Recombinant Rabbit Monoclonal Antibody [JB51-34] (ET7107-26)

UNIPROT #

Q9NPI6

PROTEIN NAME

Dcp1a

SYNONYMS

DCP1 decapping enzyme homolog A antibody;Dcp1a antibody;DCP1A_HUMAN antibody;Decapping enzyme hDcp1a antibody;Decapping mRNA 1A antibody;HSA275986 antibody;mRNA decapping enzyme 1A antibody;mRNA-decapping enzyme 1A antibody;Nbla00360 antibody;Putative protein product of Nbla00360 antibody;Smad4 interacting transcriptional co activator antibody;Smad4-interacting transcriptional co-activator antibody;Smad4-interacting transcriptional co-activator antibody;SMAD4IP1 antibody SMIF antibody;Transcription factor SMIF antibody

SEQUENCE SIMILARITIES

Belongs to the DCP1 family.

TISSUE SPECIFICITY

Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas.

SUBCELLULAR LOCATION

Cytoplasm. Nucleus.

FUNCTION

mRNA-decapping enzyme 1A is a protein that in humans is encoded by the DCP1A gene. Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. DCP1A has been shown to interact with DCP2 and UPF1. It has also been shown to colocalize with GW182, and other markers of P-body. Human DCP1A is heterotrimeric,[8] and makes contacts with the scaffold EDC3/4. The Arabidopsis thaliana homolog interacts with the plant specific type XI myosin motor protein.