CD3 epsilon Rabbit Polyclonal Antibody (ER80501)

UNIPROT #

P07766

PROTEIN NAME

CD3 epsilon

SYNONYMS

CD3 epsilon antibody;CD3e antibody;CD3e antigen epsilon polypeptide (TiT3 complex) antibody;CD3E antigen epsilon polypeptide antibody;CD3E antigen, epsilon subunit antibody;CD3e molecule epsilon antibody;CD3e molecule, epsilon (CD3 TCR complex) antibody;CD3e molecule, epsilon (CD3-TCR complex) antibody;CD3E_HUMAN antibody;IMD18 antibody;T cell antigen receptor complex epsilon subunit of T3 antibody;T cell surface antigen T3/Leu 4 epsilon chain antibody;T cell surface glycoprotein CD3 epsilon chain antibody;T-cell surface antigen T3/Leu-4 epsilon chain antibody;T-cell surface glycoprotein CD3 epsilon chain antibody;T3E antibody;TCRE antibody

POST-TRANSLATIONAL MODIFICATION

Phosphorylated on Tyr residues after T-cell receptor triggering by LCK in association with CD4/CD8.

SUBCELLULAR LOCATION

Membrane.

FUNCTION

CD3 is composed of five invariant polypeptide chains that associate to form three dimers. The five invariant chains of CD3 are labeled gamma, delta, epsilon, zeta, and eta. Each of these polypeptides contains at least one immunoreceptor tyrosine-based activation motif (ITAM) These chains associate with the T cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes.