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CNTFR Rabbit Polyclonal Antibody (HA500506)

Price: Regular price $315.00

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Catalog# HA500506

Rabbit Polyclonal to CNTFR

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

CNTFR Rabbit Polyclonal Antibody (HA500506)

Immunogen

Synthetic peptide within human cntfr aa 201-250.

Host

Rabbit

Positive Control

Mouse cerebellum tissue lysate, rat brain tissue lysate, NIH/3T3 cell lysate, human fetal skeletal muscle tissue, mouse heart tissue, Hela, SH-SY5Y.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071591

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IF-Cell

  • 1:200

  • IHC-P

  • 1:200

  • FC

  • 1:500-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 41 kDa.

Isotype

IgG

TARGET

UNIPROT #

P26992

PROTEIN NAME

CNTFR

SYNONYMS

Ciliary neurotrophic factor receptor alpha antibody;Ciliary neurotrophic factor receptor antibody;Ciliary neurotrophic factor receptor subunit alpha antibody;CNTF Receptor alpha antibody;CNTF receptor subunit alpha antibody;CNTFR Alpha antibody;CNTFR antibody;CNTFR-alpha antibody;CNTFR_HUMAN antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

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