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Calbindin Recombinant Rabbit Monoclonal Antibody [JF05-01] (ET1702-54)

Price: Regular price $385.00

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Catalog# ET1702-54

Rabbit Monoclonal to Calbindin

Tested for

  • WB

  • IF-Tissue

  • IHC-P

  • mIHC

  • IHC-Fr

Reacts with

  • Mouse

  • Rat

  • Cynomolgus monkey

  • Pig

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
This product has been cited in peer reviewed publications, see list HERE

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Calbindin Recombinant Rabbit Monoclonal Antibody [JF05-01] (ET1702-54)

Immunogen

Synthetic peptide within human calbindin aa 51-100 / 261.

Host

Rabbit

Positive Control

Mouse brain tissue lysate, rat brain tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, human kidney tissue, mouse cerebellum tissue, PC-12, 293T, rat brain tissue, mouse brain tissue, mouse kidney tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JF05-01

RRID

AB_3070316

APPLICATION DILUTION

  • WB

  • 1:1,000-1:5,000

  • IF-Tissue

  • 1:500

  • IHC-P

  • 1:5,000-1:10,000

  • mIHC

  • 1:4,000

  • IHC-Fr

  • 1:2,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 30 kDa

Isotype

IgG

TARGET

UNIPROT #

P05937

PROTEIN NAME

Calbindin

SYNONYMS

avian-type antibody;CAB27 antibody;CALB 1 antibody;CALB antibody;CALB1 antibody;CALB1_HUMAN antibody;Calbindin 1 28kDa antibody;Calbindin antibody;Calbindin D28 antibody;D 28K antibody;D-28K antibody;D28K antibody;OTTHUMP00000166027 antibody;OTTHUMP00000225441 antibody;RTVL H protein antibody;Vitamin D dependent calcium binding protein antibody;Vitamin D dependent calcium binding protein avian type antibody;Vitamin D-dependent calcium-binding protein antibody

SEQUENCE SIMILARITIES

Belongs to the calbindin family.

SUBCELLULAR LOCATION

Cytosol, Nucleus.

FUNCTION

The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 α and β, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin α and Parvalbumin β (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261 amino acid protein with six EF-hand domains, four of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

CITATIONS

  • Ogt deficiency induces abnormal cerebellar function and behavioral deficits of adult mice through modulating RhoA/ROCK signaling

  • Kaiyan Wei,et al

    FUT8 Regulates Cerebellar Neurogenesis and Development Through Maintaining the Level of Neural Cell Adhesion Molecule Cntn2

  • Caiqiao Zhang

    Improvement of eggshell quality by dietary N-carbamylglutamate supplementation in laying chickens

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