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Calpastatin Mouse Monoclonal Antibody [A6B1] (HA600072)

Price: Regular price $350.00

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Catalog# HA600072

Mouse Monoclonal to Calpastatin

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

Reacts with

  • Human

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Specifications

Product Type

Mouse monoclonal primary

Product Name

Calpastatin Mouse Monoclonal Antibody [A6B1] (HA600072)

Immunogen

Recombinant protein within human calpastatin aa 501-708 / 708.

Host

Mouse

Positive Control

A549 cell lysate, A431 cell lysate, Hela cell lysate, SiHa cell lysate A549, human esophagus tissue,.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

A6B1

RRID

AB_3071689

APPLICATION DILUTION

  • WB

  • 1:500

  • IF-Cell

  • 1:100

  • IHC-P

  • 1:200

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein G affinity purified.

Molecular Weight

Predicted band size: 120 kDa

Isotype

IgG1

TARGET

UNIPROT #

P20810

PROTEIN NAME

Calpastatin

SYNONYMS

BS 17 antibody;Calpain inhibitor antibody;Calpastatin antibody;Cast antibody;Heart type calpastatin antibody;ICAL_HUMAN antibody;MGC9402 antibody;Sperm BS 17 component antibody;Sperm BS-17 component antibody

SUBCELLULAR LOCATION

Cytosol, endoplasmic reticulum, cytoplasm, membrane.

FUNCTION

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

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