Phospho-Synapsin Ⅰ (S9) Recombinant Rabbit Monoclonal Antibody [SN63-04] (ET1611-26)

UNIPROT #

P17600

PROTEIN NAME

Phospho-Synapsin Ⅰ (S9)

SYNONYMS

Brain protein 4.1 antibody;SYN 1 antibody;SYN 1a antibody;SYN 1b antibody;SYN I antibody;SYN1 antibody;SYN1_HUMAN antibody;SYN1a antibody;SYN1b antibody;Synapsin 1 antibody;Synapsin I antibody;Synapsin-1 antibody;Synapsin1 antibody;SynapsinI antibody;SYNI antibody;Phospho-Synapsin Ⅰ (S9);Phospho Synapsin Ⅰ (S9);Phospho-Synapsin Ⅰ (S9)

SEQUENCE SIMILARITIES

Belongs to the synapsin family.

POST-TRANSLATIONAL MODIFICATION

Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal.; Phosphorylation at Ser-9 dissociates synapsins from synaptic vesicles.

SUBCELLULAR LOCATION

Cell junction, Golgi apparatus.

FUNCTION

Synapsin I, is the collective name for Synapsin Ia and Synapsin Ib, two nearly identical phosphoproteins that in humans are encoded by the SYN1 gene. In its phosphorylated form, Synapsin I may also be referred to as phosphosynaspin I. Synapsin I is the first of the proteins in the synapsin family of phosphoproteins in the synaptic vesicles present in the central and peripheral nervous systems. Synapsin Ia and Ib are close in length and almost the same in make up, however, Synapsin Ib stops short of the last segment of the C-terminal in the amino acid sequence found in Synapsin Ia.