GABA A Receptor alpha 6 Rabbit Polyclonal Antibody (HA500473)

UNIPROT #

Q16445

PROTEIN NAME

GABA A Receptor alpha 6

SYNONYMS

GABA A antibody;GABA A Receptor alpha 6 polypeptide antibody;GABA A receptor alpha 6 antibody;GABA A receptor subunit alpha 6 antibody;GABA subunit A receptor alpha 6 antibody;GABA(A) receptor subunit alpha-6 antibody;GABRA 6 antibody;GABRA6 antibody;Gamma aminobutyric acid A receptor alpha 6 antibody;Gamma aminobutyric acid GABA A receptor alpha 6 antibody;Gamma aminobutyric acid receptor subunit alpha 6 antibody;Gamma-aminobutyric acid receptor subunit alpha-6 antibody;GBRA6_HUMAN antibody;MGC116903 antibody;MGC116904 antibody

SUBCELLULAR LOCATION

Postsynaptic cell membrane, Cell membrane.

FUNCTION

Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. One study has found a genetic variant in the gene to be associated with the personality trait neuroticism.