HCLS1 Recombinant Rabbit Monoclonal Antibody [PSH01-12] (HA721624)

UNIPROT #

P14317

PROTEIN NAME

HCLS1

SYNONYMS

Cortactin like antibody;CTTNL antibody;HCLS 1 antibody;Hcls1 antibody;HCLS1_HUMAN antibody;Hematopoietic cell specific Lyn substrate 1 antibody;Hematopoietic cell-specific LYN substrate 1 antibody;Hematopoietic lineage cell-specific protein antibody;HS 1 antibody;HS1 antibody;LckBP1 antibody;OTTHUMP00000215180 antibody;OTTHUMP00000215182 antibody;p75 antibody

SUBCELLULAR LOCATION

Membrane, Cytoplasm, Mitochondrion.

FUNCTION

Hematopoietic lineage cell-specific protein is a protein that in humans is encoded by the HCLS1 gene. Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression. Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of transcription, DNA-templated. Located in cytosol; nucleus; and plasma membrane. Part of transcription regulator complex. HCLS1 has been shown to interact with Caspase 3.