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CLCNKB Rabbit Polyclonal Antibody (HA500214)

Price: Regular price $315.00

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Catalog# HA500214

Rabbit Polyclonal to CLCNKB

Tested for

  • WB

  • IHC-P

  • IF-Cell

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

CLCNKB Rabbit Polyclonal Antibody (HA500214)

Immunogen

Recombinant protein within c-terminal human clcnkb from aa520-aa687.

Host

Rabbit

Positive Control

Mouse testis tissue lysate, rat testis tissue lysate, MCF-7 cell lysate, human kidney tissue, human seminoma tissue, MG-63, A549, A431, Hela.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071311

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:100-1:500

  • IF-Cell

  • 1:50-1:100

  • FC

  • 1:500-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

75 kDa

Isotype

IgG

TARGET

UNIPROT #

P51801

PROTEIN NAME

CLCNKB

SYNONYMS

Bartter syndrome type 3 antibody;Chloride channel Kb antibody;Chloride channel kidney B antibody;Chloride channel protein ClC-Kb antibody;Chloride channel voltage sensitive Kb antibody;ClC K2 antibody;ClC-K2 antibody;ClCK2 antibody;CLCKB antibody;CLCKB_HUMAN antibody;CLCNKB antibody;hClC Kb antibody;hClCKb antibody;MGC24087 antibody;OTTHUMP00000011120 antibody;OTTHUMP00000011121 antibody;RP11 5P18.8 antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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