Skip to content

Contact

(857) 353-6600

orders@huabio.com

Collagen IV Rabbit Polyclonal Antibody (HA500197)

Price: Regular price $315.00

Volume

Bulk Order Quote   |   Customization Request

Catalog# HA500197

Rabbit Polyclonal to Collagen IV

Tested for

  • WB

  • IF-Cell

Reacts with

  • Human

This product has been cited in peer reviewed publications, see list HERE

Safety datasheet

Select your chosen country/region

Specifications

Product Type

Rabbit polyclonal primary

Product Name

Collagen IV Rabbit Polyclonal Antibody (HA500197)

Immunogen

Recombinant protein within c-terminal human collagen iv.

Host

Rabbit

Positive Control

MCF-7 cell lysate, SH-SY5Y cell lysate, SH-SY5Y.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071294

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IF-Cell

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

161 kDa

Isotype

IgG

TARGET

UNIPROT #

P02462

PROTEIN NAME

Collagen IV

SYNONYMS

Collagen alpha-1(IV) chain;Arresten;COL4A1;Collagen IV

SUBCELLULAR LOCATION

Basement membrane.

FUNCTION

This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.

CITATIONS

  • Xu Ying,et al

    Comprehensive analysis of the expression, prognostic, and immune infiltration for COL4s in stomach adenocarcinoma

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now