Skip to content

Contact

(857) 353-6600

orders@huabio.com

BMPR1A Rabbit Polyclonal Antibody (R1510-1)

Price: Regular price $315.00

Volume

Bulk Order Quote   |   Customization Request

Catalog# R1510-1

Rabbit Polyclonal to BMPR1A

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

This product has been cited in peer reviewed publications, see list HERE

Safety datasheet

Select your chosen country/region

Specifications

Product Type

Rabbit polyclonal primary

Product Name

BMPR1A Rabbit Polyclonal Antibody (R1510-1)

Immunogen

Recombinant protein within human bmpr1a aa 11-180/532.

Host

Rabbit

Positive Control

293 cell lysates, Hela, HepG2, SKOV-3, human liver carcinoma tissue, human kidney tissue, mouse skeletal muscle tissue, mouse smooth muscle tissue, mouse kidney tissue, Jurkat.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073318

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IF-Cell

  • 1:50-1:200

  • IHC-P

  • 1:50-1:200

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 60 kDa

Isotype

IgG

TARGET

UNIPROT #

P36894

PROTEIN NAME

BMPR1A

SYNONYMS

10q23del antibody;Activin A receptor type II like kinase 3 antibody;Activin receptor like kinase 3 antibody;Activin receptor-like kinase 3 antibody;ACVRLK 3 antibody;ACVRLK3 antibody;ALK 3 antibody;ALK-3 antibody;ALK3 antibody;BMP type-1A receptor antibody;BMPR 1A antibody;Bmpr antibody;BMPR-1A antibody;Bmpr1a antibody;BMR1A_HUMAN antibody;Bone morphogenetic protein receptor type IA antibody;Bone morphogenetic protein receptor type IA precursor antibody;Bone morphogenetic protein receptor type-1A antibody;BR 1a antibody;BR1a antibody;CD 292 antibody;CD292 antibody;CD292 antigen antibody;EC 2.7.11.30 antibody;Serine threonine protein kinase receptor R5 antibody;Serine threonine protein kinase receptor R5 precursor antibody;Serine/threonine-protein kinase receptor R5 antibody;SKR 5 antibody;SKR5 antibody;zBMPR IA antibody;zBMPRIA antibody

SEQUENCE SIMILARITIES

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

TISSUE SPECIFICITY

Highly expressed in skeletal muscle.

POST-TRANSLATIONAL MODIFICATION

Glycosylated.

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.

CITATIONS

  • Lei, S. S., Huang, X. W., Li, L. Z., Wang, X. P., Zhang, Y., Li, B., & Shou, D.

    Explorating the mechanism of Epimedii folium-Rhizoma drynariae herbal pair promoted bone defects healing through network pharmacology and experimental studies

  • Yuling Mi; Caiqiao Zhang

    The Attenuating Effect of the Intraovarian Bone Morphogenetic Protein 4 on Age-Related Endoplasmic Reticulum Stress in Chicken Follicular Cells

  • Total Flavonoids from Rhizoma Drynariae (Gusuibu) Alleviates Diabetic Osteoporosis by Activating BMP2/Smad Signaling Pathway

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now