ALDH7A1 Recombinant Rabbit Monoclonal Antibody [JE63-38] (HA720086)

UNIPROT #

P49419

PROTEIN NAME

ALDH7A1

SYNONYMS

26g turgor protein homolog antibody;AL7A1_HUMAN antibody;Aldehyde dehydrogenase 7 A1 antibody;Aldehyde dehydrogenase 7 family, member A1 antibody;Aldehyde dehydrogenase family 7 member A1 antibody;ALDH7A1 antibody;Alpha AASA dehydrogenase antibody;Alpha aminoadipic semialdehyde dehydrogenase antibody;Alpha-AASA dehydrogenase antibody;Alpha-aminoadipic semialdehyde dehydrogenase antibody;Antiquitin 1 antibody;Antiquitin antibody;Antiquitin-1 antibody;ATQ1 antibody;Betaine aldehyde dehydrogenase antibody;Delta1 piperideine 6 carboxylate dehydrogenease antibody;Delta1-piperideine-6-carboxylate dehydrogenase antibody;EPD antibody;P6c dehydrogenase antibody;PDE antibody

SUBCELLULAR LOCATION

Cytoplasm, Mitochondrion, Nucleus.

FUNCTION

The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.