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MTHFD2 Rabbit Polyclonal Antibody (ER2001-62)

Price: Regular price $315.00

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Catalog# ER2001-62

Rabbit Polyclonal to MTHFD2

Tested for

  • WB

  • FC

Reacts with

  • Human

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

MTHFD2 Rabbit Polyclonal Antibody (ER2001-62)

Immunogen

Synthetic peptide within human mthfd2 aa 300-350.

Host

Rabbit

Positive Control

293 cell lysates, Daudi.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3069539

APPLICATION DILUTION

  • WB

  • 1:500

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

38 kDa

Isotype

IgG

TARGET

UNIPROT #

P13995

PROTEIN NAME

MTHFD2

SYNONYMS

Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial antibody;Descriptions antibody;Methenyltetrahydrofolate cyclohydrolase antibody;methylene tetrahydrofolate dehydrogenase (NAD+ dependent) antibody;methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 antibody;methylenetetrahydrofolate dehydrogenase (NADP+ dependent) antibody;methylenetetrahydrofolate dehydrogenase 2 antibody;MGC82516 antibody;MTDC_HUMAN antibody;MTHFD2 antibody;mthfd2 methylene tetrahydrofolate dehydrogenase (NAD+ dependent) antibody;NAD-dependent methylene tetrahydrofolate dehydrogenase antibody;NAD-dependent methylenetetrahydrofolate dehydrogenase antibody;NMDMC antibody

SUBCELLULAR LOCATION

Mitochondrion.

FUNCTION

Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial is an enzyme that in humans is encoded by the MTHFD2 gene. This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

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