PPP1CA Rabbit Polyclonal Antibody (HA500074)

UNIPROT #

P62136

PROTEIN NAME

PPP1CA

SYNONYMS

Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit antibody;Catalytic subunit antibody;EC 3.1.3.16 antibody;MGC15877 antibody;MGC1674 antibody;PP 1A antibody;PP-1A antibody;PP1A antibody;PP1A_HUMAN antibody;PP1alpha antibody;PP2C ALPHA antibody;PP2CA antibody;Ppp1ca antibody;Protein Phosphatase 2C Alpha Isoform antibody;Serine threonine protein phosphatase PP1 alpha catalytic subunit antibody;Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1 antibody;Serine/threonine-protein phosphatase PP1-alpha catalytic subunit antibody

SUBCELLULAR LOCATION

Nucleus, nucleoplasm, nucleolus, cytoplasm.

FUNCTION

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.