PPP2R4 Rabbit Polyclonal Antibody (HA500123)

UNIPROT #

Q15257

PROTEIN NAME

PPP2R4

SYNONYMS

subunit B'' antibody;KIAA0044 antibody;MGC2184 antibody;Phosphotyrosyl phosphatase activator antibody;PP2A antibody;PP2A phosphatase activator antibody;PP2A subunit B' antibody;PP2A subunit B' isoform PR53 antibody;PP2A subunit B' PR53 isoform antibody;PPP2R4 antibody;PR53 antibody;PR53 isoform antibody;Protein phosphatase 2, regulatory subunit B-prime antibody;Protein phosphatase 2A activator regulatory subunit 4 antibody;Protein phosphatase 2A regulatory subunit B' (PR 53) antibody;PTPA antibody;PTPA_HUMAN antibody;Serine/threonine protein phosphatase 2A regulatory subunit B' antibody;Serine/threonine-protein phosphatase 2A activator antibody;Serine/threonine-protein phosphatase 2A regulatory subunit 4 antibody;Serine/threonine-protein phosphatase 2A regulatory subunit B'' antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.