PPP2R5D Recombinant Rabbit Monoclonal Antibody [PSH01-22] (HA721639)

UNIPROT #

Q14738

PROTEIN NAME

PPP2R5D

SYNONYMS

2A5D_HUMAN antibody;B'delta antibody;B56D antibody;Delta isoform of regulatory subunit B56, protein phosphatase 2A antibody;MGC2134 antibody;MGC8949 antibody;OTTHUMP00000039821 antibody;PP2A B subunit B' delta isoform antibody;PP2A B subunit B56 delta isoform antibody;PP2A B subunit isoform B''-delta antibody;PP2A B subunit isoform B56-delta antibody;PP2A B subunit isoform PR61-delta antibody;PP2A B subunit isoform R5-delta antibody;PP2A B subunit PR61 delta isoform antibody;PP2A B subunit R5 delta isoform antibody;PPP2R5D antibody;Protein phosphatase 2 regulatory subunit B (B56) delta isoform antibody;Protein phosphatase 2 regulatory subunit B delta isoform antibody;Protein phosphatase 2 regulatory subunit B' delta antibody;Serine threonine protein phosphatase 2A 56 kDa regulatory subunit delta isoform antibody;Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform antibody;TEG-271 antibody;Tex271 antibody

SUBCELLULAR LOCATION

Cytoplasm, Nucleus.

FUNCTION

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the PPP2R5D gene. Mutations in PPP2R5D cause Jordan's Syndrome. The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.