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Hsp22 Recombinant Rabbit Monoclonal Antibody [JJ08-53] (ET1701-11)

Price: Regular price $385.00

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Catalog# ET1701-11

Rabbit Monoclonal to Hsp22

Tested for

  • WB

  • IF-Cell

  • IF-Tissue

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Safety datasheet

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Hsp22 Recombinant Rabbit Monoclonal Antibody [JJ08-53] (ET1701-11)

Immunogen

Synthetic peptide within human hsp22 aa 1-50 / 196.

Host

Rabbit

Positive Control

HepG2 cell lysate, mouse skeletal muscle tissue lysate, Hela, A431, SH-SY5Y, mouse brain tissue, rat skeletal muscle tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JJ08-53

RRID

AB_3070178

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IF-Cell

  • 1:100-1:500

  • IF-Tissue

  • 1:100-1:500

  • IHC-P

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 22 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9UJY1

PROTEIN NAME

Hsp22

SYNONYMS

Alpha crystallin C chain antibody;Alpha-crystallin C chain antibody;Charcot Marie Tooth disease axonal type 2L antibody;Charcot Marie Tooth disease spinal antibody;CMT2L antibody;CRYAC antibody;DHMN 2 antibody;DHMN2 antibody;E2 induced gene 1 protein antibody;E2-induced gene 1 protein antibody;E2IG1 antibody;H11 antibody;Heat shock 22kDa protein 8 antibody;Heat shock 27kDa protein 8 antibody;Heat shock protein 22 antibody;Heat shock protein beta 8 antibody;Heat shock protein beta-8 antibody;Hereditary motor neuropathy distal antibody;HMN 2 antibody;HMN2 antibody;HMN2A antibody;HSB8 antibody;HSPB 8 antibody;HspB8 antibody;HSPB8_HUMAN antibody;OTTHUMP00000239768 antibody;Protein kinase H11 antibody;Small stress protein like protein HSP22 antibody;Small stress protein-like protein HSP22 antibody;Spinal muscular atrophy distal adult autosomal dominant antibody

SEQUENCE SIMILARITIES

Belongs to the small heat shock protein (HSP20) family.

TISSUE SPECIFICITY

Predominantly expressed in skeletal muscle and heart.

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. Mutations in this gene have been associated with an autosomal dominant rimmed vacuolar myopathy The clinical features of this condition are distal and proximal myopathy. MRI show severe relatively symmetric multifocal fatty degenerative changes within the muscles. Muscle biopsy shows rimmed vacuoles, muscle fiber atrophy and endomysial fibrosis.

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