PDE4B Recombinant Rabbit Monoclonal Antibody [JE33-95] (HA722323)

UNIPROT #

Q07343

PROTEIN NAME

PDE4B

SYNONYMS

5''-cyclic phosphodiesterase 4B antibody;cAMP-specific 3'' antibody;cAMP-specific 3',5'-cyclic phosphodiesterase 4B antibody;cAMP-specific phosphodiesterase-4 B isoform antibody;DKFZp686F2182 antibody;DPDE4 antibody;dunce-like phosphodiesterase E4 antibody;MGC126529 antibody;OTTHUMP00000010652 antibody;OTTHUMP00000010653 antibody;OTTHUMP00000010654 antibody;OTTHUMP00000010656 antibody;OTTHUMP00000232365 antibody;PDE 4B antibody;PDE IVB antibody;PDE32 antibody;Pde4b antibody;PDE4B_HUMAN antibody;PDE4B5 antibody;PDEIVB antibody;Phosphodiesterase 4B antibody;Phosphodiesterase 4B cAMP specific antibody;Phosphodiesterase 4B, cAMP specific (phosphodiesterase E4 dunce homolog, Drosophila) antibody

SUBCELLULAR LOCATION

Cytoplasm, Cell membrane.

FUNCTION

cAMP-specific 3',5'-cyclic phosphodiesterase 4B is an enzyme that in humans is encoded by the PDE4B gene. This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.