Annexin A3 Mouse Monoclonal Antibody [A1F7] (EM1901-73)

UNIPROT #

P12429

PROTEIN NAME

Annexin A3

SYNONYMS

2-cyclic phosphate 2-phosphohydrolase antibody;35-alpha calcimedin antibody;Annexin A3 antibody;Annexin III antibody;Annexin-3 antibody;ANX3 antibody;ANXA 3 antibody;Anxa3 antibody;ANXA3_HUMAN antibody;Calcimedin 35 alpha antibody;Inositol 1 2 cyclic phosphate 2 phosphohydrolase antibody;Inositol 1 antibody;Lipocortin III antibody;OTTHUMP00000160701 antibody;OTTHUMP00000219237 antibody;OTTHUMP00000219238 antibody;PAP III antibody;PAP-III antibody;Placental anticoagulant protein III antibody

SEQUENCE SIMILARITIES

Belongs to the annexin family.

SUBCELLULAR LOCATION

Cytosol, extracellular exosome, plasma membrane, axon, cytoplasm, dendrite, membrane, neuronal cell body, phagocytic vesicle membrane, specific granule.

FUNCTION

Annexin A3 is a protein that in humans is encoded by the ANXA3 gene. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.