Annexin A3 Rabbit Polyclonal Antibody (ER1802-50)

UNIPROT #

P12429

PROTEIN NAME

Annexin A3

SYNONYMS

2-cyclic phosphate 2-phosphohydrolase antibody;35-alpha calcimedin antibody;Annexin A3 antibody;Annexin III antibody;Annexin-3 antibody;ANX3 antibody;ANXA 3 antibody;Anxa3 antibody;ANXA3_HUMAN antibody;Calcimedin 35 alpha antibody;Inositol 1 2 cyclic phosphate 2 phosphohydrolase antibody;Inositol 1 antibody;Lipocortin III antibody;OTTHUMP00000160701 antibody;OTTHUMP00000219237 antibody;OTTHUMP00000219238 antibody;PAP III antibody;PAP-III antibody;Placental anticoagulant protein III antibody

SEQUENCE SIMILARITIES

Belongs to the annexin family.

SUBCELLULAR LOCATION

Cytoplasm. Secreted. Plasma Membrane.

FUNCTION

The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-α calcimedin or ANX3, belongs to the annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.