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UTF1 Mouse Monoclonal Antibody [E0-F4] (M1407-6)

Price: Regular price $350.00

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Catalog# M1407-6

Mouse Monoclonal to UTF1

Tested for

  • WB

  • IF-Cell

Reacts with

  • Human

  • Mouse

  • Rat

This product has been cited in peer reviewed publications, see list HERE

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Specifications

Product Type

Mouse monoclonal primary

Product Name

UTF1 Mouse Monoclonal Antibody [E0-F4] (M1407-6)

Immunogen

Synthetic peptide within human utf1 aa 51-100 / 341.

Host

Mouse

Positive Control

D3

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

E0-F4

RRID

AB_3073087

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IF-Cell

  • 1:500-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein A affinity purified.

Molecular Weight

36-50 kDa

Isotype

IgG2b

TARGET

UNIPROT #

Q5T230

PROTEIN NAME

UTF1

SYNONYMS

hUTF 1 antibody;hUTF1 antibody;Undifferentiated embryonic cell transcription factor 1 antibody;UTF 1 antibody;UTF1 antibody;UTF1_HUMAN antibody

POST-TRANSLATIONAL MODIFICATION

Phosphorylated.

SUBCELLULAR LOCATION

Nucleus

FUNCTION

Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is localized to the cell nucleus, where it functions to regulate the pluripotent chromatin state and buffer mRNA levels by promoting degradation of mRNA. Aberrant expression of UTF1 has also been reported in cervical cancer cells, where the UTF1 gene promoter loses methylation and becomes abnormally expressed compared to normal cervical cells.

CITATIONS

  • Ying Zheng

    Stimulated by retinoic acid gene 8 (Stra8) plays important roles in many stages of spermatogenesis

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