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CD105 Rabbit Polyclonal Antibody (HA500266)

Price: Regular price $315.00

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Catalog# HA500266

Rabbit Polyclonal to CD105

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

CD105 Rabbit Polyclonal Antibody (HA500266)

Immunogen

Recombinant protein within human cd105 aa 100-300 / 658 (extracellular).

Host

Rabbit

Positive Control

Hela cell lysates, human spleen tissue, human placenta tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071362

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:100-1:500

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

71 kDa

Isotype

IgG

TARGET

UNIPROT #

P17813

PROTEIN NAME

CD105

SYNONYMS

AI528660 antibody;AI662476 antibody;CD 105 antibody;CD105 antibody;CD105 antigen antibody;EGLN_HUMAN antibody;END antibody;Endoglin antibody;Eng antibody;FLJ41744 antibody;HHT1 antibody;ORW antibody;ORW1 antibody;Osler Rendu Weber syndrome 1 antibody;RP11 228B15.2 antibody;S endoglin antibody;S-endoglin antibody;SN6 antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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