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GFAP Rabbit Polyclonal Antibody (R1308-10)

Price: Regular price $315.00

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Catalog# R1308-10

Rabbit Polyclonal to GFAP

Tested for

  • WB

  • IF-Cell

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

This product has been cited in peer reviewed publications, see list HERE

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

GFAP Rabbit Polyclonal Antibody (R1308-10)

Immunogen

Synthetic peptide within c-terminal residues of gfap.

Host

Rabbit

Positive Control

Human brain, A172, mouse brain tissue lysate, rat brain tissue lysate.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073229

APPLICATION DILUTION

  • WB

  • 1:5,000-1:10,000

  • IF-Cell

  • 1:50-1:100

  • IHC-P

  • 1:200

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 50 kDa

Isotype

IgG

TARGET

UNIPROT #

P14136

PROTEIN NAME

GFAP

SYNONYMS

wu:fb34h11 antibody;ALXDRD antibody;cb345 antibody;etID36982.3 antibody;FLJ42474 antibody;FLJ45472 antibody;GFAP antibody;GFAP_HUMAN antibody;gfapl antibody;Glial fibrillary acidic protein antibody;Intermediate filament protein antibody;wu:fk42c12 antibody;xx:af506734 antibody;zgc:110485 antibody

SEQUENCE SIMILARITIES

Belongs to the intermediate filament family.

TISSUE SPECIFICITY

Expressed in cells lacking fibronectin.

POST-TRANSLATIONAL MODIFICATION

Phosphorylated by PKN1.

SUBCELLULAR LOCATION

Cytoplasm, Intermediate filament.

FUNCTION

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. In addition, GFAP intermediate filaments are also present in nonmyelin-forming Schwann cells in the peripheral nervous system.

CITATIONS

  • Xudong Pan,et al

    Lnc_011797 promotes ferroptosis and aggravates white matter lesions

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