AK6 Rabbit Polyclonal Antibody (R1406-1)

UNIPROT #

Q9Y3D8

PROTEIN NAME

AK6

SYNONYMS

AD-004 antibody;Adenylate kinase isoenzyme 6 antibody;Adrenal gland protein AD-004 antibody;AK/ATPase antibody;AK6 antibody;CGI-137 antibody;CIP antibody;Coilin-interacting nuclear ATPase protein antibody;Dual activity adenylate kinase/ATPase antibody;hCINAP antibody;KAD6_HUMAN antibody;TAF9 antibody

SEQUENCE SIMILARITIES

Belongs to the adenylate kinase family. AK6 subfamily.

TISSUE SPECIFICITY

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.

SUBCELLULAR LOCATION

Nucleus

FUNCTION

Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. AK6 may have a role in nuclear energy homeostasis. It has also ATPase activity and may be involved in regulation of Cajal body (CB) formation.