Alkaline Phosphatase Mouse Monoclonal Antibody [6-10] (M0806-10)
Catalog# M0806-10
Mouse Monoclonal to Alkaline Phosphatase
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WB
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IHC-P
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FC
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Human
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Mouse
Specifications
Product Type
Mouse monoclonal primary
Product Name
Alkaline Phosphatase Mouse Monoclonal Antibody [6-10] (M0806-10)
Immunogen
Synthetic peptide within human alkaline phosphatase aa 350-450.
Host
Mouse
Positive Control
Hela, mouse ovary
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
6-10
RRID
APPLICATION DILUTION
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WB
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1:5,000-1:10,000
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IHC-P
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1:200
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2ug/ul
Purification
Protein A affinity purified.
Molecular Weight
58 kDa
Isotype
IgG2b
TARGET
UNIPROT #
PROTEIN NAME
Alkaline Phosphatase
SYNONYMS
Alkaline phosphatase antibody;Alkaline phosphatase placental antibody;Alkaline phosphatase placental type antibody;Alkaline phosphatase Regan isozyme antibody;ALP antibody;Alp1 antibody;ALPP antibody;FLJ61142 antibody;Germ-cell alkaline phosphatase antibody;nagao isozyme antibody;OTTHUMP00000164354 antibody;PALP antibody;Placental alkaline phosphatase 1 antibody;placental heat-stable alkaline phosphatase antibody;placental type antibody;PLAP antibody;PLAP-1 antibody;PLAP1 antibody;PPB1_HUMAN antibody
SEQUENCE SIMILARITIES
Belongs to the alkaline phosphatase family.
TISSUE SPECIFICITY
Detected in placenta (at protein level).
SUBCELLULAR LOCATION
cell membrane
FUNCTION
Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Placental ALP is highly polymorphic, there are at least three common alleles. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
CITATIONS
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Bone marrow mesenchymal stem cell-derived exosomes loaded with miR-26a through the novel immunomodulatory peptide DP7-C can promote osteogenesis
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WB
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Rat
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Citation
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Neuronal TRPV1-CGRP axis regulates bone defect repair through Hippo signaling pathway
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WB
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Mouse
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Citation
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GDNF promotes the proliferation and osteogenic differentiation of jaw bone marrow mesenchymal stem cells via the Nr4a1/PI3K/Akt pathway
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IF-cell
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Human
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Citation
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