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CHD3 Recombinant Rabbit Monoclonal Antibody [JE57-05] (HA720011)

Price: Regular price $385.00

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Catalog# HA720011

Rabbit Monoclonal to CHD3

Tested for

  • WB

  • IHC-P

  • FC

Reacts with

  • Human

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

CHD3 Recombinant Rabbit Monoclonal Antibody [JE57-05] (HA720011)

Immunogen

Recombinant protein within human chd3 aa 1,850-2,000.

Host

Rabbit

Positive Control

SiHa cell lysates, human thyroid tissue, human breast carcinoma tissue, human fallopian tube tissue, human uterus tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JE57-05

RRID

AB_3071952

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:200-1:500

  • FC

  • 1:500-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 227 kDa.

Isotype

IgG

TARGET

UNIPROT #

Q12873

PROTEIN NAME

CHD3

SYNONYMS

226 antibody;2600010P09Rik antibody;AF020312 antibody;ATP dependent helicase CHD3 antibody;ATP-dependent helicase Chd3 antibody;CHD-3 antibody;Chd3 antibody;CHD3_HUMAN antibody;Chd7 antibody;Chromodomain-helicase-DNA-binding protein 3 antibody;hZFH antibody;MGC40857 antibody;Mi 2 autoantigen 240 kDa protein antibody;Mi 2a antibody;Mi-2 autoantigen 240 kDa protein antibody;Mi2 ALPHA antibody;Mi2-alpha antibody;Prp7 antibody;Prp9 1 antibody;ZFH antibody;Zinc finger helicase antibody;zinc-finger helicase (Snf2-like) antibody

SUBCELLULAR LOCATION

Centrosome, Nucleus.

FUNCTION

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

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