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DOPEY2 Rabbit Polyclonal Antibody (0903-3)

Price: Regular price $315.00

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Catalog# 0903-3

Rabbit Polyclonal to DOPEY2

Tested for

  • WB

  • IF-Cell

  • IHC-P

  • FC

Reacts with

  • Human

  • Mouse

This product has been cited in peer reviewed publications, see list HERE

Specifications

Product Type

Rabbit polyclonal primary

Product Name

DOPEY2 Rabbit Polyclonal Antibody (0903-3)

Immunogen

Synthetic peptide within human dopey2 aa 1025-1074 / 2,298.

Host

Rabbit

Positive Control

Mouse heart, human heart, Siha, N2A, Mouse brain,

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3068700

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

  • IF-Cell

  • 1:50-1:500

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 258kDa

Isotype

IgG

TARGET

UNIPROT #

Q9Y3R5

PROTEIN NAME

DOPEY2

SYNONYMS

Dipeptidase 2 antibody;Dipeptidase2 antibody;DPEP 2 antibody;MBD 2 antibody;MBD2 antibody

SEQUENCE SIMILARITIES

Belongs to the dopey family.

TISSUE SPECIFICITY

Ubiquitously expressed. Overexpressed in lymphoblasts from Down syndrome patients.

DEVELOPMENTAL STAGE

Abundantly expressed in developing central nervous system, with highest levels in cerebellum and lowest in telencephalon.

SUBCELLULAR LOCATION

Early endosome membrane, Golgi apparatus membrane.

FUNCTION

Dopey-2, a 2,298 amino acid protein, belongs to the dopey family, that is overexpressed in lymphoblasts from Down syndrome patients and Abundantly expressed in developing central nervous system, with highest levels in cerebellum and lowest in telencephalon. Multiple isoforms of Dopey-2 exist due to alternative splicing events. Dopey-2 is thought to play a role in protein trafficking between early endosomes and the late.

CITATIONS

  • Dopey2 and Pcdh7 orchestrate the development of embryonic neural stem cells/ progenitors in zebrafish

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