FABP3 Recombinant Rabbit Monoclonal Antibody [JE53-37] (HA721859)

UNIPROT #

P05413

PROTEIN NAME

FABP3

SYNONYMS

422 protein antibody;Cardiac FABP antibody;Cardiac Fatty Acid Binding Protein antibody;FABP 11 antibody;FABP 3 antibody;FABP11 antibody;FABP3 antibody;FABPH_HUMAN antibody;Fatty acid binding protein 11 antibody;Fatty acid binding protein 3 antibody;Fatty acid binding protein 3 muscle and heart antibody;Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor antibody;Fatty acid binding protein 3 muscle antibody;Fatty acid binding protein 3, muscle and heart (mammary derived growth inhibitor) antibody;Fatty acid binding protein 3, muscle antibody;Fatty acid binding protein heart antibody;Fatty acid binding protein, heart antibody;Fatty acid binding protein, muscle and heart antibody;Fatty acid binding protein, skeletal muscle antibody;Fatty acid-binding protein 3 antibody;Fatty acid-binding protein antibody;H FABP antibody;H-FABP antibody;heart antibody;Heart type fatty acid binding protein antibody;Heart-type fatty acid-binding protein antibody;M FABP antibody;M-FABP antibody;Mammary derived growth inhibitor antibody;Mammary-derived growth inhibitor antibody;MDGI antibody;Muscle fatty acid binding protein antibody;Muscle fatty acid-binding protein antibody;Mylein protein P2 homolog antibody;O FABP antibody;OTTHUMP00000003898 antibody;P2 adopocyte protein antibody

SUBCELLULAR LOCATION

Cytoplasm.

FUNCTION

Heart-type Fatty Acid-Binding Protein (H-FABP) is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. See FABP3 for biochemical details. The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer.