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FIP200 Mouse Monoclonal Antibody [A9A9] (HA601106)

Price: Regular price $350.00

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Catalog# HA601106

Mouse Monoclonal to FIP200

Tested for

  • WB

  • IHC-P

  • IF-Cell

Reacts with

  • Human

  • Rat

  • Mouse

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Specifications

Product Type

Mouse monoclonal primary

Product Name

FIP200 Mouse Monoclonal Antibody [A9A9] (HA601106)

Immunogen

Recombinant protein within human rb1cc1 aa 651-800 / 1,594.

Host

Mouse

Positive Control

Hela cell lysate, MCF-7 cell lysate, 293T cell lysate, rat kidney tissue, human kidney tissue, Hela.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

A9A9

RRID

AB_3071828

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IHC-P

  • 1:200-1:1,000

  • IF-Cell

  • 1:200

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1.21ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 183 kDa

Isotype

IgG1

TARGET

UNIPROT #

Q8TDY2

PROTEIN NAME

FIP200

SYNONYMS

FAK family kinase-interacting protein of 200 kDa antibody;FIP200 antibody;RB1-inducible coiled-coil protein 1 antibody;RB1CC1 antibody;RBCC1_HUMAN antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm, Cytoplasm, cytosol, Lysosome.

FUNCTION

FIP200 (FAK family kinase-interacting protein of 200 kDa) was identified in a two-hybrid screen with the tyrosine kinase Pyk2 and can inhibit Pyk2 kinase activity as well as related family members. FIP200 was later independently identified in a multi-drug resistance screen and named RB1CC1 (RB1-inducible coiled-coil 1) due to its induction by cytotoxic stress and RB1 expression regulation. FIP200 function has been linked to apoptosis, cell cycle progression, cell growth, and migration. FIP200 has also recently been shown to interact with ULK1 and is required for autophagosome formation. FIP200 is part of an ULK1 complex along with Atg13 that is regulated by mTOR and is required for starvation induced autophagy.

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