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FITC Conjugated Human CD11b Recombinant Mouse Monoclonal Antibody [A2-9-R] (HA600130F)

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Catalog# HA600130F

Mouse Monoclonal to Human CD11b

Tested for

  • FC

Reacts with

  • Human

  • Mouse

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free
Conjugated to FITC

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Specifications

Product Type

Recombinant Mouse monoclonal primary

Product Name

FITC Conjugated Human CD11b Recombinant Mouse Monoclonal Antibody [A2-9-R] (HA600130F)

Immunogen

Recombinant protein within human cd11b aa 544-743 / 1,152.

Host

Mouse

Positive Control

Mouse peripheral blood.

Conjugation

Fitc

Clonality

Monoclonal

Clone Number

A2-9-R

APPLICATION DILUTION

  • FC

  • 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

PROPERTIES

Form

Liquid

Storage Condition

Store at 2C to 8C. Avoid repeated freeze / thaw cycles.

Storage Buffer

Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.

Concentration

/

Purification

Protein G affinity purified.

Molecular Weight

Predicted band size: 127 kDa

Isotype

IgG1

TARGET

UNIPROT #

P11215

PROTEIN NAME

Human CD11b

SYNONYMS

antigen CD11b (p170) antibody;Antigen CD11b p170 antibody;CD11 antigen like family member B antibody;CD11 antigen-like family member B antibody;CD11b antibody;CD11b/CD18 antibody;CD49d antibody;Cell surface glycoprotein MAC-1 subunit alpha antibody;Complement component 3 receptor 3 subunit antibody;Complement Component Receptor 3 Alpha antibody;Complement receptor type 3, alpha subunit antibody;CR 3 alpha chain (CR3A) antibody;CR 3 alpha chain antibody;CR-3 alpha chain antibody;CR3 antibody;CR3A antibody;F730045J24Rik antibody;Integrin Alpha M antibody;Integrin alpha M chain antibody;Integrin alpha-M antibody;Integrin beta 2 alpha subunit antibody;Integrin subunit alpha M antibody;integrin, alpha M (complement component 3 receptor 3 subunit) antibody;ITAM_HUMAN antibody;ITGAM antibody;Leukocyte adhesion receptor MO1 antibody;Ly-40 antibody;MAC 1 antibody;Mac-1a antibody;MAC1 antibody;Mac1, alpha subunit antibody;MAC1A antibody;Macrophage antigen alpha polypeptide antibody;MGC117044 antibody;Mo1, alpha subunit antibody;MO1A antibody;Neutrophil adherence receptor alpha M subunit antibody;Neutrophil adherence receptor antibody;SLEB6 antibody

SUBCELLULAR LOCATION

Cell membrane.

FUNCTION

Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development.

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