FosB Recombinant Rabbit Monoclonal Antibody [SN703] (ET1611-75)
Catalog# ET1611-75
Rabbit Monoclonal to FosB
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WB
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IHC-P
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IP
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Human
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Mouse
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Rat
Lysates/proteins at 10 µg/Lane.
Predicted band size: 36 kDa
Observed band size: 40 kDa
Exposure time: 2 minutes;
12% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (ET1611-75) at 1/500 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 1 hour at room temperature.
Specifications
Product Type
Recombinant Rabbit monoclonal primary
Product Name
FosB Recombinant Rabbit Monoclonal Antibody [SN703] (ET1611-75)
Immunogen
Recombinant protein within human fosb aa 6-189 / 338.
Host
Rabbit
Positive Control
SK-Br-3 cell lysates, human tonsil tissue, mouse hippocampus tissue, mouse brain tissue, mouse spleen tissue, rat spleen tissue.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
SN703
RRID
APPLICATION DILUTION
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WB
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1:500-1:1,000
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IHC-P
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1:50-1:2,000
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IP
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Use at an assay dependent concentration.
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Protein A affinity purified.
Molecular Weight
Predicted band size: 36 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
FosB
SYNONYMS
Activator protein 1 antibody;AP 1 antibody;DKFZp686C0818 antibody;FBJ murine osteosarcoma viral oncogene homolog B antibody;fosB antibody;FOSB_HUMAN antibody;G0/G1 switch regulatory protein 3 antibody;G0S3 antibody;GOS 3 antibody;GOS B antibody;GOS3 antibody;GOSB antibody;MGC42291 antibody;Oncogene FOS B antibody;Oncogene FOSB antibody;Protein fos B antibody;Protein fosB antibody
SEQUENCE SIMILARITIES
Belongs to the bZIP family. Fos subfamily.
SUBCELLULAR LOCATION
Nucleus.
FUNCTION
The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.
CITATIONS
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Resveratrol Alleviates Levodopa-Induced Dyskinesia in Rats
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WB
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IHC
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Rat
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Citation
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