Fyn Recombinant Rabbit Monoclonal Antibody [JE42-22] (HA721577)

UNIPROT #

P06241

PROTEIN NAME

Fyn

SYNONYMS

C syn protooncogene antibody;Fyn antibody;FYN oncogene related to SRC FGR YES antibody;FYN_HUMAN antibody;OKT3 induced calcium influx regulator antibody;P59 FYN antibody;p59-Fyn antibody;Protein tyrosine kinase fyn antibody;Proto oncogene tyrosine protein kinase fyn antibody;Proto-oncogene c-Fyn antibody;Proto-oncogene Syn antibody;Protooncogene Syn antibody;SLK antibody;Src like kinase antibody;Src yes related novel gene antibody;Src-like kinase antibody;Src/yes related novel antibody;SYN antibody;Tyrosine kinase p59fyn T antibody;Tyrosine kinase p59fyn(T) antibody;Tyrosine-protein kinase Fyn antibody

SUBCELLULAR LOCATION

Cytoplasm, Nucleus, Cell membrane, Perikaryon.

FUNCTION

Proto-oncogene tyrosine-protein kinase Fyn (p59-FYN, Slk, Syn, MGC45350, Gene ID 2534) is an enzyme that in humans is encoded by the FYN gene. Fyn is a 59-kDa member of the Src family of kinases typically associated with T-cell and neuronal signaling in development and normal cell physiology. Disruptions in these signaling pathways often have implications in the formation of a variety of cancers. By definition as a proto-oncogene, Fyn codes for proteins that help regulate cell growth. Changes in its DNA sequence transform it into an oncogene that leads to the formation of a different protein with implications for normal cell regulation. Fyn is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.