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HNF1 alpha Rabbit Polyclonal Antibody (HA500285)

Price: Regular price $315.00

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Catalog# HA500285

Rabbit Polyclonal to HNF1 alpha

Tested for

  • WB

  • IHC-P

  • FC

Reacts with

  • Human

  • Mouse

  • Rat

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

HNF1 alpha Rabbit Polyclonal Antibody (HA500285)

Immunogen

Recombinant protein within human hnf1 alpha aa 100-300 / 631.

Host

Rabbit

Positive Control

HepG2 cell lysate, mouse uterus tissue lysate, human kidney tissue lysate, rat kidney tissue, human small intestine tissue, mouse liver tissue, HepG2.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071380

APPLICATION DILUTION

  • WB

  • 1:1,000-1:5,000

  • IHC-P

  • 1:100-1:500

  • FC

  • 1:500-1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

67 kDa

Isotype

IgG

TARGET

UNIPROT #

P20823

PROTEIN NAME

HNF1 alpha

SYNONYMS

Albumin proximal factor antibody;Hepatic nuclear factor 1 alpha antibody;Hepatic nuclear factor 1 antibody;Hepatic transcription factor 1 alpha antibody;Hepatic transcription factor 1 antibody;Hepatocyte nuclear factor 1-alpha antibody;HNF 1 antibody;HNF 1A antibody;HNF-1-alpha antibody;HNF-1A antibody;hnf1a antibody;HNF1A_HUMAN antibody;Interferon production regulator factor antibody;LF B1 antibody;LF B1 hepatic nuclear factor antibody;LFB 1 antibody;LFB1 antibody;LFB1 hepatic nuclear factor antibody;Liver specific transcription factor LF B1 antibody;Liver specific transcription factor LFB1 antibody;Liver-specific transcription factor LF-B1 antibody;Maturity onset diabetes of the young 3 antibody;MODY 3 antibody;MODY3 antibody;TCF 1 antibody;TCF-1 antibody;TCF1 antibody;Transcription factor 1 antibody;Transcription factor 1 hepatic antibody

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

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