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Human IL-33 ELISA Kit ( EH0047)

Price: Regular price $499.00

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Catalog# EH0047

Assay type Sandwich ELISA

Range 1.37~1000 pg/ml

Sensitivity 0.76 pg/ml (50 μl)；1.25 pg/ml (10 μl)

PERFORMANCE CHARACTERISTICS

Sensitivity

0.76 pg/ml (50 μl)；1.25 pg/ml (10 μl)

Range

1.37~1000 pg/ml

Recovery

The spike recovery was evaluated by spiking 3 levels of human IL-33 into health human serum sample. The un-spiked serum was used as blank in this experiment. The recovery ranged from 99% to 127% with an overall mean recovery of 108%.

Specifications

Product Type

ELISA Kit

Product Name

Human IL-33 ELISA Kit ( EH0047)

Detection method

Colorimetric

Sample type

Serum

Assay type

Sandwich ELISA

Category

Fully Ready-to-Use

PROPERTIES

Storage instructions

Store at +4C

Kits Components

Coated Plate

96 well

Standard

9 vial

Detect Antibody

6 ml/bottle

Streptavidin-HRP

12 ml/bottle

Assay Buffer

12 ml/bottle

Stop Solution

12 ml/bottle

Wash Buffer

50 ml/bottle

Sealer Film

6 pieces

TARGET

UNIPROT #

O95760

PROTEIN NAME

IL-33

FUNCTION

IL-33 (Interleukin-33) is released from physically damaged or necrotic cells. It triggers Th2-biased immune cell activation at sites of inflammation as well as regulatory T cell and M2 macrophage expansion. It additionally induces angiogenesis, promotes tumor cell migration and invasion, limits cardiac myocyte hypertrophy, and limits the development of atherosclerotic plaques. IL-33 signals through a receptor complex composed of ST2 and IL-1 RAcP. IL-1 RAcP also associates with IL-1 RI, IL-1 RII, IL-1 R6, and SCF R/c-kit. Soluble isoforms of ST2 and IL-1 RAcP function as decoy receptors that regulate IL-33 bioactivity.

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