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Human PDGF-AA, Tag Free Protein (Active) (HA211046)

Price: Regular price $379.00

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Catalog# HA211046

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  • Human

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Product Details

Product Type

Protein

Product Name

Human PDGF-AA, Tag Free Protein (Active) (HA211046)

Predicted molecular mass

22.4 kD

Protein construction description

A DNA sequence encoding the human PDGF-AA protein (P04085-1) (Glu 21-Thr 211) which RRKR sequence from 83 to 86 is mutated into GGGS was expressed with tag free.

Accession

P04085-1

Protein construction

PDGF-AA (21-211)(RRKR(83-86)GGGS)

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20C to -80C It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

Reconstitution

Reconstitute at 250 μg/ml in sterile water.

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