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Human uPAR enzyme-linked immunoassay kit(EH0077)

Price: Regular price $499.00

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Catalog# EH0077

Assay type Sandwich ELISA

Range 27.43~20000 pg/ml

Sensitivity 8.79 pg/ml (50 μl)

PERFORMANCE CHARACTERISTICS

Sensitivity

8.79 pg/ml (50 μl)

Range

27.43~20000 pg/ml

Recovery

The spike recovery was evaluated by spiking 3 levels of human uPAR into health human serum sample. The un-spiked serum was used as blank in this experiment. The recovery ranged from 80% to 103% with an overall mean recovery of 96%.

Specifications

Product Type

ELISA Kit

Product Name

Human uPAR enzyme-linked immunoassay kit(EH0077)

Detection method

Colorimetric

Sample type

Serum

Assay type

Sandwich ELISA

Category

PROPERTIES

Storage instructions

Store at +4℃

Kits Components

Coated Plate

96 well

Standard

9 vial

Detect Antibody

6 ml/bottle

Streptavidin-HRP

12 ml/bottle

Assay Buffer

12 ml/bottle

Stop Solution

12 ml/bottle

Wash Buffer

50 ml/bottle

Sealer Film

6 pieces

TARGET

UNIPROT #

Q03405

PROTEIN NAME

uPAR

SYNONYMS

Urokinase plasminogen activator surface receptor U-PAR uPAR Monocyte activation antigen Mo3 CD87 PLAUR MO3 UPAR

FUNCTION

The urokinase-type Plasminogen Activator Receptor (uPAR) is a GPI-anchored protein that binds to both the inactive and active forms of uPA. This interaction serves to localize and enhance the proteolytic activity of uPA, leading to increased conversion of Plasminogen to Plasmin. uPA also triggers uPAR-mediated signal transduction, activation of protein tyrosine kinases, gene expression, cell adhesion, and chemotaxis. uPAR can additionally regulate cell adhesion by direct binding to Vitronectin and preventing Integrins from binding to their ligands.

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