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IL-5 Rabbit Polyclonal Antibody (HA500081)

Price: Regular price $315.00

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Catalog# HA500081

Rabbit Polyclonal to IL-5

Tested for

  • WB

  • IF-Cell

  • ELISA

Reacts with

  • Human

This product has been cited in peer reviewed publications, see list HERE

Specifications

Product Type

Rabbit polyclonal primary

Product Name

IL-5 Rabbit Polyclonal Antibody (HA500081)

Immunogen

Synthetic peptide within human il-5 aa 60-110.

Host

Rabbit

Positive Control

LOVO cell lysates, LOVO cells.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071180

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IF-Cell

  • 1:50-1:200

  • ELISA

  • 1:5,000-1:10,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 15 kDa

Isotype

IgG

TARGET

UNIPROT #

P05113

PROTEIN NAME

IL-5

SYNONYMS

B-cell differentiation factor I antibody;Colony stimulating factor antibody;EDF antibody;Eosinophil differentiation factor antibody;IL-5 antibody;IL5 antibody;IL5_HUMAN antibody;Interleukin 5 (colony stimulating factor, eosinophil) antibody;Interleukin 5 antibody;Interleukin-5 antibody;T Cell Replacing Factor antibody;T-cell replacing factor antibody;TRF antibody

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells.Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion - primarily IgA. It is also a key mediator in eosinophil activation.IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer.

CITATIONS

  • Zhang Dong,et al

    TNFSF11/TNFRSF11A Axis Amplifies HDM-Induced Airway Remodeling by Strengthening TGFβ1/STAT3 Action

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