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IRX2 Rabbit Polyclonal Antibody (R1307-5)

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Catalog# R1307-5

Rabbit Polyclonal to IRX2

Tested for

  • WB

  • IF-Cell

Reacts with

  • Human

  • Mouse

Specifications

Product Type

Rabbit polyclonal primary

Product Name

IRX2 Rabbit Polyclonal Antibody (R1307-5)

Immunogen

Synthetic peptide corresponding to human irx2 aa 422-471 / 471.

Host

Rabbit

Positive Control

Hela cell lysate, HepG2 cell lysate, SiHa cell lysate, Hela.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3073224

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IF-Cell

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 49 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9BZI1

PROTEIN NAME

IRX2

SYNONYMS

Homeodomain protein IRXA2 antibody;Iroquois homeobox 2 antibody;Iroquois homeobox protein 2 antibody;Iroquois-class homeodomain protein irx-2 antibody;IRX 2 antibody;irx2 antibody;IRX2_HUMAN antibody;IrxA2 antibody

SEQUENCE SIMILARITIES

Belongs to the TALE/IRO homeobox family.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

Iroquois-class homeodomain protein IRX-2, also known as Iroquois homeobox protein 2, is a protein that in humans is encoded by the IRX2 gene. IRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos. IRX2 gene has been observed progressively downregulated in Human papillomavirus-positive neoplastic keratinocytes derived from uterine cervical preneoplastic lesions at different levels of malignancy. For this reason, IRX2 is likely to be associated with tumorigenesis and may be a potential prognostic marker for uterine cervical preneoplastic lesions progression.

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