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Mesothelin Recombinant Rabbit Monoclonal Antibody [PSH02-30] (HA721810)

Price: Regular price $385.00

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Catalog# HA721810

Rabbit Monoclonal to Mesothelin

Tested for

  • WB

  • IF-Cell

  • IF-Tissue

  • IHC-P

Reacts with

  • Human

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Mesothelin Recombinant Rabbit Monoclonal Antibody [PSH02-30] (HA721810)

Immunogen

Recombinant protein within human mesothelin aa 273-622 / 622 (q13421-3).

Host

Rabbit

Positive Control

SiHa cell lysate, NCI-H226 cell lysate, HeLa cell lysate, NIH:OVCAR-3 cell lysate, NCI-H226, human ovarian carcinoma tissue, human tonsil tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

PSH02-30

RRID

AB_3072922

APPLICATION DILUTION

  • WB

  • 1:1,000

  • IF-Cell

  • 1:100

  • IF-Tissue

  • 1:100

  • IHC-P

  • 1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 68 kDa

Isotype

IgG

TARGET

UNIPROT #

Q13421

PROTEIN NAME

Mesothelin

SYNONYMS

CAK 1 antibody;CAK1 antibody;CAK1 antigen antibody;cleaved form antibody;Megakaryocyte potentiating factor antibody;Mesothelin antibody;Mesothelin isoform 1 precursor antibody;MPF antibody;Msln antibody;MSLN_HUMAN antibody;Pre pro megakaryocyte potentiating factor antibody;Pre-pro-megakaryocyte-potentiating factor antibody;SMR antibody;SMRP antibody;Soluble MPF mesothelin related protein antibody

SUBCELLULAR LOCATION

Cell membrane, Golgi apparatus; Secreted.

FUNCTION

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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